Biointerfacing polymeric microcapsules for in vivo near-infrared light-triggered drug release.

Near-infrared light-responsive graphene oxide composite multilayer capsules: a novel route for remote controlled drug delivery.

A novel and simple route for near-infrared (NIR)-light controlled release of drugs has been demonstrated using graphene oxide (GO) composite microcapsules based on the unique optical properties of GO. Upon NIR-laser irradiation, the microcapsules were ruptured in a point-wise fashion due to local heating which in turn triggers the light-controlled release of the encapsulated anticancer drug dox...

Autonomous Indication of Mechanical Damage in Polymeric Coatings.

High-resolution in situ autonomous visual indication of mechanical damage is achieved through a microcapsule-based polymeric material system. Upon mechanical damage, ruptured microcapsules release a liquid indicator molecule. A sharp color change from light yellow to bright red is triggered when the liberated indicator 2',7'-dichlorofluorescein reacts with the polymeric coating matrix.

Use of laser-triggered gold nanoparticle-grafted dual light and temperature-responsive polymeric sensor for the recognition of thioguanine as anti-tumor agent

Objective(s): Today, there is an urgent need for improved sensor materials for drug sensing and effective monitoring and interventions in this area are highly required to struggle drug abuse. The present study aimed to synthesize a thioguanine-responsive sensor based on a nanocomposite consisting of AuNP-grafted light- and temperature-responsive poly butylmethacrylate-co-acrylamide-co-methacryl...

Magnetically triggered release of molecular cargo from iron oxide nanoparticle loaded microcapsules.

Photothermal release of cargo molecules has been extensively studied for bioapplications. For instance, microcapsules decorated with plasmonic nanoparticles have been widely used in in vitro assays. However, some concerns about their suitability for some in vivo applications cannot be easily overcome, in particular the limited penetration depth of light (even infrared). Magnetic nanoparticles a...

Biodegradable polymeric microcapsules for selective ultrasound-triggered drug release